Relationships Between Biological Heavy Metals and Breast Cancer: A Systematic Review and Meta-Analysis.

ABSTRACT:

Introduction

Heavy metals were classified as essential, probably essential, and potentially toxic in the general population. Until now, it has been reported inconsistently on the association between heavy metals and BC. In this meta-analysis, we aimed to assess the association between heavy metals and BC and review the potential mechanisms systematically.

Methods

We searched for epidemiological studies in English about the association between heavy metals and BC published before September 2020 in PubMed, Web of Science, and Embase databases. In total 36 studies, comprising 4,151 individuals from five continents around the world were identified and included.

Results

In all biological specimens, Cu, Cd, and Pb concentrations were higher, but Zn and Mn concentrations wer

SUBMITTER: Liu L 

PROVIDER: S-EPMC9245072 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature