Malignancy in ankylosing spondylitis: a cross-sectional analysis of a large population database.

ABSTRACT:

Background

Increased cancer-risk has been reported with rheumatoid arthritis and systemic lupus erythematosus, but the risk is poorly studied in ankylosing spondylitis (AS). Conflicting data in AS have been reported in Asia and Europe, with lack of US population-based studies. Our objective is to study the prevalence of cancer in patients with AS in the US.

Methods

Using the Explorys database, we performed a cross-sectional study. Data from AS patients and controls were stratified by 2 rheumatology visits, age groups, clinical characteristics, and frequency of cancers. The data were analyzed using a series of chi-square tests of independence as well as logistic regression to test for association between AS and cancer.

Results

1410 AS patients (12.88%) had cancer. Fema

SUBMITTER: Bittar M 

PROVIDER: S-EPMC9245256 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature