Risk Factors Associated With Lower Bone Mineral Density in Primary Aldosteronism Patients.

ABSTRACT:

Purpose

The association between primary aldosteronism (PA) and lower bone mineral density (BMD) has raised a concern, but the contributing factors remain unclear. We aim to explore the risk factors for lower BMD in PA patients.

Methods

We analyzed and compared the data of 60 PA patients with 60 matched essential hypertension (EH) patients. BMD, bone metabolites, and several oxidative stress and inflammation indicators-including C-reactive protein (CRP), superoxide dismutase (SOD), total bilirubin (TBIL), mean platelet volume (MPV), etc.-were assessed and compared in PA and EH patients. Bivariate correlation analysis and multivariate linear regression analysis were performed to explore the factors associated with BMD in PA patients.

Results

The BMD measured by q

SUBMITTER: Lv X 

PROVIDER: S-EPMC9245341 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature