HIV viral load assays when used with whole blood perform well as a diagnostic assay for infants.

ABSTRACT:

Objective

Over the past several years, only approximately 50% of HIV-exposed infants received an early infant diagnosis test within the first two months of life. While high attrition and mortality account for some of the shortcomings in identifying HIV-infected infants early and putting them on life-saving treatment, fragmented and challenging laboratory systems are an added barrier. We sought to determine the accuracy of using HIV viral load assays for infant diagnosis of HIV.

Methods

We enrolled 866 Ugandan infants between March-April 2018 for this study after initial laboratory diagnosis. The median age was seven months, while 33% of infants were less than three months of age. Study testing was done using either the Roche or Abbott molecular technologies at the Central Pu

SUBMITTER: Kiyaga C 

PROVIDER: S-EPMC9246233 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature