A yeast cell cycle model integrating stress, signaling, and physiology.

ABSTRACT: The cell division cycle in eukaryotic cells is a series of highly coordinated molecular interactions that ensure that cell growth, duplication of genetic material, and actual cell division are precisely orchestrated to give rise to two viable progeny cells. Moreover, the cell cycle machinery is responsible for incorporating information about external cues or internal processes that the cell must keep track of to ensure a coordinated, timely progression of all related processes. This is most pronounced in multicellular organisms, but also a cardinal feature in model organisms such as baker's yeast. The complex and integrative behavior is difficult to grasp and requires mathematical modeling to fully understand the quantitative interplay of the single components within the entire system. Her

SUBMITTER: Adler SO 

PROVIDER: S-EPMC9246278 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature