Insights from two independent transcriptomic studies of the bovine corpus luteum during pregnancy.

ABSTRACT: Several recent studies have used transcriptomics to investigate luteal changes during the maternal recognition of the pregnancy period in ruminants. Although these studies have contributed to our understanding of luteal function during early pregnancy, few attempts have been made to integrate information across these studies and distinguish key luteal transcripts or functions that are repeatably identified across multiple studies. Therefore, in this study, two independent studies of the luteal transcriptome during early pregnancy were combined and compared. In the first study, corpora lutea (CL) from day 20 of pregnancy were compared with CL collected on day 14 of pregnancy, prior to embryonic signaling. The cattle were nonlactating. In the second study, CL from day 20 of pregnancy were co

SUBMITTER: Hughes CHK 

PROVIDER: S-EPMC9246655 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature