SUCCOR Risk: Design and Validation of a Recurrence Prediction Index for Early-Stage Cervical Cancer.

ABSTRACT:

Objective

Based on the SUCCOR study database, our primary objective was to identify the independent clinical pathological variables associated with the risk of relapse in patients with stage IB1 cervical cancer who underwent a radical hysterectomy. Our secondary goal was to design and validate a risk predictive index (RPI) for classifying patients depending on the risk of recurrence.

Methods

Overall, 1116 women were included from January 2013 to December 2014. We randomly divided our sample into two cohorts: discovery and validation cohorts. The test group was used to identify the independent variables associated with relapse, and with these variables, we designed our RPI. The index was applied to calculate a relapse risk score for each participant in the validation group.

SUBMITTER: Manzour N 

PROVIDER: S-EPMC9246807 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature