Identification of Hypoxia-Related Subtypes, Establishment of Prognostic Models, and Characteristics of Tumor Microenvironment Infiltration in Colon Cancer.
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ABSTRACT:
SUBMITTER: Wang C
PROVIDER: S-EPMC9247151 | biostudies-literature | 2022
REPOSITORIES: biostudies-literature
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Identification of Hypoxia-Related Subtypes, Establishment of Prognostic Models, and Characteristics of Tumor Microenvironment Infiltration in Colon Cancer.
Wang Changjing C Tang Yujie Y Ma Hongqing H Wei Sisi S Hu Xuhua X Zhao Lianmei L Wang Guiying G
Frontiers in genetics 20220617
<b>Background:</b> Immunotherapy is a treatment that can significantly improve the prognosis of patients with colon cancer, but the response to immunotherapy is different in patients with colon cancer because of the heterogeneity of colon carcinoma and the complex nature of the tumor microenvironment (TME). In the precision therapy mode, finding predictive biomarkers that can accurately identify immunotherapy-sensitive types of colon cancer is essential. Hypoxia plays an important role in tumor ...[more]
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