Global Burden and Trends of Norovirus-Associated Diseases From 1990 to 2019: An Observational Trend Study.

ABSTRACT:

Introduction

As an important pathogen causing diarrheal diseases, the burden and change in the death rate of norovirus-associated diseases (NADs) globally are still unknown.

Methods

Based on global disease burden data from 1990 to 2019, we analyzed the age-standardized death rate (ASDR) of NADs by age, region, country, and Socio-Demographic Index (SDI) level. The discrete Poisson model was applied in the analysis of NADs' spatiotemporal aggregation, the Joinpoint regression model to analyze the trend of death burden of NADs over 30 years, and a generalized linear model to identify the risk factors for the death rate from NADs.

Results

The ASDR of NADs significantly decreased by a factor of approximately 2.7 times, from 5.02 (95% CI: 1.1, 11.34) in 1990 to 1.86 (95% CI

SUBMITTER: Zhang X 

PROVIDER: S-EPMC9247406 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature