Association of Posttraumatic Stress Disorder With Accelerated Cognitive Decline in Middle-aged Women.

ABSTRACT:

Importance

Posttraumatic stress disorder (PTSD) has been hypothesized to lead to impaired cognitive function. However, no large-scale studies have assessed whether PTSD is prospectively associated with cognitive decline in middle-aged adults.

Objective

To assess the association between PTSD and decline in cognitive function over time.

Design, setting, and participants

This cohort study included participants from the Nurses' Health Study II, an ongoing longitudinal cohort study involving community-dwelling middle-aged female nurses residing in the US who had at least a 2-year nursing degree at the time of enrollment in 1989. The present study included 12 270 trauma-exposed women who were enrolled in the PTSD substudy of the Nurses' Health Study II and completed 1 to 5

SUBMITTER: Roberts AL 

PROVIDER: S-EPMC9247738 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature