Burden of Congenital and Hereditary Anomalies in Hazara Population of Khyber Pakhtunkhwa, Pakistan.

ABSTRACT:

Background and objectives

In Pakistan, there is high incidence of congenital and hereditary anomalies (CA) which are a leading cause of infant mortality and morbidity. In order to elucidate the burden and biodemographic correlates of CA, this study was aimed to report the prevalence-pattern and phenotypic attributes of CA in the Hazara population of Khyber Pakhtunkhwa, Pakistan.

Methods

In a retrospective cross-sectional study, subjects/families with CA were recruited from district hospitals and community centers. Phenotypic and descriptive data were obtained; pedigrees were analyzed and parental and biodemographic attributes were recorded.

Results

A total of 1,189 independent subjects and/or families with CA were ascertained. The malformations were grouped into nine

SUBMITTER: Bibi A 

PROVIDER: S-EPMC9247803 | biostudies-literature | 2022 May-Jun

REPOSITORIES: biostudies-literature