Correlation between crown-rump length in the first trimester of pregnancy and neonatal outcomes.

ABSTRACT:

Background

To investigate the association of crown-rump length (CRL) during the first trimester of pregnancy with neonatal outcomes.

Methods

A total of 15,524 women with a reliable first day of the last menstrual period and a regular menstrual cycle (28 ± 4 days) were included from January 2015 to November 2016. CRL was measured by ultrasound from 7⁺⁰ to 13⁺⁶ weeks during pregnancy and transformed to a standard deviation score (SDS) adjusted for gestational age. Linear regression was used to explore risk factors for CRL. A generalised linear model was used to evaluate the association between CRL and neonatal outcomes.

Results

In the multivariate analysis, maternal age (0.25 mm, 95% CI = [0.22-0.28], P < 0.001; 0.04 SDS, 95% CI = [0.03-0.04], P < 

SUBMITTER: Xu Y 

PROVIDER: S-EPMC9248167 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature