Mediation effects of thyroid function in the associations between phthalate exposure and lipid metabolism in adults.

ABSTRACT: Phthalates are a group of industrial chemicals widely used in everyday products including cosmetics, food packaging and containers, plastics, and building materials. Previous studies have indicated that urinary phthalate metabolites are associated with metabolic effects including those on lipid metabolism, but the results are mixed. Furthermore, whether thyroid function mediates the association between phthalate exposure and lipid metabolism remains unclear. In the present study, we explored whether changes in thyroid function markers mediate the associations between phthalate exposure and lipid metabolism indicators in Taiwanese adults. The cross-sectional data were obtained from the Taiwan Environmental Survey for Toxicants conducted in 2013. Levels of 11 urinary phthalate metabolites, l

SUBMITTER: Huang HB 

PROVIDER: S-EPMC9248169 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature