Critical factors in achieving fine-scale functional MRI: Removing sources of inadvertent spatial smoothing.

ABSTRACT: Ultra-high Field (≥7T) functional magnetic resonance imaging (UHF-fMRI) provides opportunities to resolve fine-scale features of functional architecture such as cerebral cortical columns and layers, in vivo. While the nominal resolution of modern fMRI acquisitions may appear to be sufficient to resolve these features, several common data preprocessing steps can introduce unwanted spatial blurring, especially those that require interpolation of the data. These resolution losses can impede the detection of the fine-scale features of interest. To examine quantitatively and systematically the sources of spatial resolution losses occurring during preprocessing, we used synthetic fMRI data and real fMRI data from the human visual cortex-the spatially interdigitated human V2 "thin" and "thick" st

SUBMITTER: Wang J 

PROVIDER: S-EPMC9248309 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature