Categorizing Comorbid Risk for People Living With HIV: A Latent Profile Analysis.

ABSTRACT:

Background

Categorizing clinical risk amidst heterogeneous multimorbidity in older people living with HIV/AIDS (PLWH) may help prioritize and optimize health care engagements.

Methods

PLWH and their prevalent conditions in 8 health domains diagnosed before January 1, 2015 were identified using 2014-2016 Medicare claims and the Chronic Conditions Data Warehouse. Latent profile analysis identified 4 distinct clinical subgroups based on the likelihood of conditions occurring together [G1: healthy, G2: substance use (SU), G3: pulmonary (PULM), G4: cardiovascular conditions (CV)]. Restricted mean survival time regression estimated the association of each subgroup with the 365 day mean event-free days until death, first hospitalization, and nursing home admission. Zero-inflated Po

SUBMITTER: Olivieri-Mui B 

PROVIDER: S-EPMC9248847 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature