Ontology highlight
ABSTRACT:
SUBMITTER: Meuwese RTC
PROVIDER: S-EPMC9249610 | biostudies-literature | 2023 Feb
REPOSITORIES: biostudies-literature
Meuwese Rob T C RTC Versteeg Elly M M EMM van Drongelen Joris J de Hoog Daniëlle D Bouwhuis Debora D Vandenbussche Frank P H A FPHA van Kuppevelt Toin H TH Daamen Willeke F WF
Bioactive materials 20220624
Iatrogenic preterm premature rupture of fetal membranes (iPPROM) after fetal surgery remains a strong trigger for premature birth. As fetal membrane defects do not heal spontaneously and amniotic fluid leakage and chorioamniotic membrane separation may occur, we developed a biocompatible, fetoscopically-applicable collagen plug with shape memory to prevent leakage. This plug expands directly upon employment and seals fetal membranes, hence preventing amniotic fluid leakage and potentially iPPROM ...[more]