Analysis of Outcomes Associated With Outpatient Management of Nonoperatively Treated Patients With Appendicitis.

ABSTRACT:

Importance

In the Comparison of Outcomes of Antibiotic Drugs and Appendectomy (CODA) trial, which found antibiotics to be noninferior, approximately half of participants randomized to receive antibiotics had outpatient management with hospital discharge within 24 hours. If outpatient management is safe, it could increase convenience and decrease health care use and costs.

Objective

To assess the use and safety of outpatient management of acute appendicitis.

Design, setting, and participants

This cohort study, which is a secondary analysis of the CODA trial, included 776 adults with imaging-confirmed appendicitis who received antibiotics at 25 US hospitals from May 1, 2016, to February 28, 2020.

Exposures

Participants randomized to antibiotics (intravenous then

SUBMITTER: Writing Group for the CODA Collaborative 

PROVIDER: S-EPMC9250049 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature