Genetically Predicted Milk Intake Increased Femoral Neck Bone Mineral Density in Women But Not in Men.

ABSTRACT:

Background

Cow milk contains more calcium, magnesium, potassium, zinc, and phosphorus minerals. For a long time, people have believed that increasing milk intake is beneficial to increasing bone density. Many confounding factors can affect milk consumption, and thus the association described to date may not be causal. We explored the causal relationship between genetically predicted milk consumption and Bone Mineral Density (BMD) of the femoral neck and lumbar spine based on 53,236 individuals from 27 studies of European ancestry using the Mendelian randomization (MR) study. 32,961 individuals of European and East Asian ancestry were used for sensitivity analysis.

Methods

A genetic instrument used for evaluating milk consumption is rs4988235, a locus located at 13,910 base p

SUBMITTER: Chen S 

PROVIDER: S-EPMC9251187 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature