Evaluation of Antiradical and Antioxidant Activities of Lipopeptides Produced by Bacillus subtilis Strains.

ABSTRACT: This study investigated the antiradical and antioxidant potential of the three families of lipopeptides (i.e., surfactin, mycosubtilin, and plipastatin/fengycin) produced by Bacillus subtilis strains. The antiradical/antioxidant activities of highly purified lipopeptides were studied in acellular models using a 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical, superoxide anion ( O2.- ), hydrogen peroxide, (H₂O₂) and hydroxyl radical (HO^.). At a lipopeptide concentration of 500 mg.L^-1, the maximum inhibition of DPPH reached 22.88% (obtained for plipastatin). Moreover, the scavenging effects of O2.- , H₂O₂, and HO^. at the highest concentration tested (250 mg.L^-1) were found to be 6, 21, and 3% for surf

SUBMITTER: Dussert E 

PROVIDER: S-EPMC9251515 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature