Agomelatine for the treatment of generalized anxiety disorder: focus on its distinctive mechanism of action.
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ABSTRACT:
SUBMITTER: Millan MJ
PROVIDER: S-EPMC9251978 | biostudies-literature | 2022
REPOSITORIES: biostudies-literature
Publications
Agomelatine for the treatment of generalized anxiety disorder: focus on its distinctive mechanism of action.
Therapeutic advances in psychopharmacology 20220630
Generalized anxiety disorder (GAD), the most frequently diagnosed form of anxiety, is usually treated by cognitive-behavioural approaches or medication; in particular, benzodiazepines (acutely) and serotonin or serotonin/noradrenaline reuptake inhibitors (long term). Efficacy, compliance, and acceptability are, however, far from ideal, reinforcing interest in alternative options. Agomelatine, clinically employed in the treatment of major depression, expresses anxiolytic properties in rodents and ...[more]
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