Survival benefits from neoadjuvant treatment in gastric cancer: a systematic review and meta-analysis.

ABSTRACT:

Background

Surgery is the main treatment option for patients with local gastric cancer. However, surgery alone is usually not sufficient for stomach cancer patients, and combined therapies are recommended for these patients. In recent studies, some preoperative treatments have shown benefits. However, the treatment selection is still uncertain because previous studies failed to obtain a statistically significant difference between preoperative chemotherapy and preoperative chemoradiotherapy. Therefore, we plan to perform a systematic review and meta-analysis to compare the benefits among these preoperative treatments.

Methods/design

This review includes randomized controlled trials with or without blinding as well as published studies, high-quality unpublished studies, full

SUBMITTER: Hu J 

PROVIDER: S-EPMC9252040 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature