TWIN-10: protocol for a 10-year longitudinal twin study of the neuroscience of mental well-being and resilience.

ABSTRACT:

Introduction

Mental well-being is a core component of mental health, and resilience is a key process of positive adaptive recovery following adversity. However, we lack an understanding of the neural mechanisms that contribute to individual variation in the trajectories of well-being and resilience relative to risk. Genetic and/or environmental factors may also modulate these mechanisms. The aim of the TWIN-10 Study is to characterise the trajectories of well-being and resilience over 12 years across four timepoints (baseline, 1 year, 10 years, 12 years) in 1669 Australian adult twins of European ancestry (to account for genetic stratification effects). To this end, we integrate data across genetics, environment, psychological self-report, neurocognitive performance and brain funct

SUBMITTER: Park HRP 

PROVIDER: S-EPMC9252211 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature