Ontology highlight
ABSTRACT:
SUBMITTER: Han S
PROVIDER: S-EPMC9252272 | biostudies-literature | 2022 Jul
REPOSITORIES: biostudies-literature
Han Shunhua S Dias Guilherme B GB Basting Preston J PJ Nelson Michael G MG Patel Sanjai S Marzo Mar M Bergman Casey M CM
Genetics 20220701 3
Cultured cells are widely used in molecular biology despite poor understanding of how cell line genomes change in vitro over time. Previous work has shown that Drosophila cultured cells have a higher transposable element content than whole flies, but whether this increase in transposable element content resulted from an initial burst of transposition during cell line establishment or ongoing transposition in cell culture remains unclear. Here, we sequenced the genomes of 25 sublines of Drosophil ...[more]