GeCoViz: genomic context visualisation of prokaryotic genes from a functional and evolutionary perspective.

ABSTRACT: Synteny conservation analysis is a well-established methodology to investigate the potential functional role of unknown prokaryotic genes. However, bioinformatic tools to reconstruct and visualise genomic contexts usually depend on slow computations, are restricted to narrow taxonomic ranges, and/or do not allow for the functional and interactive exploration of neighbouring genes across different species. Here, we present GeCoViz, an online resource built upon 12 221 reference prokaryotic genomes that provides fast and interactive visualisation of custom genomic regions anchored by any target gene, which can be sought by either name, orthologous group (KEGGs, eggNOGs), protein domain (PFAM) or sequence. To facilitate functional and evolutionary interpretation, GeCoViz allows to customise t

SUBMITTER: Botas J 

PROVIDER: S-EPMC9252766 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature