SubcellulaRVis: a web-based tool to simplify and visualise subcellular compartment enrichment.

ABSTRACT: Cells contain intracellular compartments, including membrane-bound organelles and the nucleus, and are surrounded by a plasma membrane. Proteins are localised to one or more of these cellular compartments; the correct localisation of proteins is crucial for their correct processing and function. Moreover, proteins and the cellular processes they partake in are regulated by relocalisation in response to various cellular stimuli. High-throughput 'omics experiments result in a list of proteins or genes of interest; one way in which their functional role can be understood is through the knowledge of their subcellular localisation, as deduced through statistical enrichment for Gene Ontology Cellular Component (GOCC) annotations or similar. We have designed a bioinformatics tool, named Subcellul

SUBMITTER: Watson J 

PROVIDER: S-EPMC9252817 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature