Thoracic Aortic ¹⁸F-Sodium Fluoride Activity and Ischemic Stroke in Patients With Established Cardiovascular Disease.

ABSTRACT:

Background

Aortic atherosclerosis represents an important contributor to ischemic stroke risk. Identifying patients with high-risk aortic atheroma could improve preventative treatment strategies for future ischemic stroke.

Objectives

The purpose of this study was to investigate whether thoracic ¹⁸F-sodium fluoride positron emission tomography (PET) could improve the identification of patients at the highest risk of ischemic stroke.

Methods

In a post hoc observational cohort study, we quantified thoracic aortic and coronary ¹⁸F-sodium fluoride activity in 461 patients with stable cardiovascular disease undergoing PET combined with computed tomography (CT). Progression of atherosclerosis was assessed by change in aortic and coronary CT calcium volu

SUBMITTER: Fletcher AJ 

PROVIDER: S-EPMC9252920 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature