Pharmacologic therapies of pain in patients with spinal cord injury: a systematic review.

ABSTRACT:

Study design

Systematic review.

Objectives

This systematic review evaluates all randomized clinical trials (RCTs) conducted on assessing the efficacy and safety of pharmacologic therapies for the treatment of Spinal Cord Injury (SCI)-associated pain.

Methods

The PubMed/Medline, EMBASE, and Cochrane library online databases were searched from 1946 to May 2019 using specific search terms for SCI, pain, and RCTs meeting predetermined inclusion criteria. The efficacy outcome of interest was pain reduction, discontinuations, and adverse events (AEs).

Results

Of 2746 records identified through database searching, 703 duplicates were deleted. 1814 were excluded, the full text of the remaining 230 articles was reviewed, and finally, 28 papers were selected for drafting

SUBMITTER: Asgardoon MH 

PROVIDER: S-EPMC9253022 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature