Fatal non-traumatic gas gangrene caused by Clostridium perfringens type A in a Siberian Husky dog.

ABSTRACT: An 8-y-old, castrated male Siberian Husky dog was admitted to an emergency clinic with acute collapse and severe swelling of both forelimbs, ventral thorax, and axillary region. The clinical assessment, with laboratory tests and radiologic investigation, confirmed severe subcutaneous emphysema and multi-organ failure. The animal died while receiving emergency treatment. On postmortem examination, Clostridium perfringens was isolated from the subcutaneous fluid and the effusion from the thoracic and abdominal cavities. Relevant histopathology findings included subcutaneous emphysema and multi-organ perivascular and intravascular, intralesional myriad 0.5-3-µm gram-positive rod bacteria, with no associated inflammation. Whole-genome sequencing and phylogenetic analysis identified C

SUBMITTER: Sprohnle-Barrera CH 

PROVIDER: S-EPMC9254053 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature