Identification of potential key molecules and signaling pathways for psoriasis based on weighted gene co-expression network analysis.

ABSTRACT:

Background

Psoriasis is a chronic inflammatory skin disease, the pathogenesis of which is more complicated and often requires long-term treatment. In particular, moderate to severe psoriasis usually requires systemic treatment. Psoriasis is also associated with many diseases, such as cardiometabolic diseases, malignant tumors, infections, and mood disorders. Psoriasis can appear at any age, and lead to a substantial burden for individuals and society. At present, psoriasis is still a treatable, but incurable, disease. Previous studies have found that microRNAs (miRNAs) play an important regulatory role in the progression of various diseases. Currently, miRNAs studies in psoriasis and dermatology are relatively new. Therefore, the identification of key miRNAs in psoriasis is helpful

SUBMITTER: Shu X 

PROVIDER: S-EPMC9254198 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature