Physiological and transcriptomic responses of Chlorella sorokiniana to ciprofloxacin reveal molecular mechanisms for antibiotic removal.

ABSTRACT: Microalgae-based technology is an effective and environmentally friendly method for antibiotics-contaminated wastewater treatment. To assess the tolerance and removal ability of Chlorella sorokiniana to ciprofloxacin (CIP), this study comprehensively revealed the responses of C. sorokiniana to CIP exposure and its degradation processes through physiological and transcriptomic analyses. Although the photosynthetic system was inhibited, the growth of C. sorokiniana was not negatively affected by CIP. Dissolved organic matter was analyzed and indicated that humic-like substances were released to alleviate the stress of CIP. In addition, the maximum removal of CIP was 83.3% under 20 mg L^-1 CIP exposure. HPLC-MS/MS and RNA-Seq analyses suggested that CIP could be

SUBMITTER: Li Z 

PROVIDER: S-EPMC9254343 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature