Diagnostic accuracy of ultrasound, CT and their combination in detecting cervical lymph node metastasis in patients with papillary thyroid cancer: a systematic review and meta-analysis.

ABSTRACT:

Objectives

To determine the diagnostic accuracy of ultrasound (US), CT and their combination in detecting cervical lymph node metastasis (CLNM) in patients with papillary thyroid cancer (PTC).

Methods

Medline (via PubMed), Web of Science, Embase were searched to identify studies published till 5 December 2021 that used US and CT to detect CLNM in patients with PTC. The primary outcomes were sensitivity, specificity and diagnostic ORs in neck-level-based (lymph nodes are analysed by neck level) or patient-based (lymph nodes are analysed by patient) analysis. Secondary outcomes were sensitivity, specificity and DORs in the central and lateral compartments.

Results

Fourteen studies (6167 patients with 11 601 neck lymph nodes) met the inclusion criteria. Based on the neck

SUBMITTER: Yang J 

PROVIDER: S-EPMC9255397 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature