Adverse drug reactions, multimorbidity and polypharmacy: a prospective analysis of 1 month of medical admissions.

ABSTRACT:

Objective

To ascertain the burden and associated cost of adverse drug reactions (ADRs), polypharmacy and multimorbidity through a prospective analysis of all medical admissions to a large university teaching hospital over a 1-month period.

Design

Prospective observational study.

Setting

Liverpool University Hospital Foundation National Health Service (NHS) Trust, England.

Participants

All medical admissions with greater than 24-hour stay over a 1-month period.

Main outcome measures

Prevalence of admissions due to an ADR and associated mortality, prevalence and association of multimorbidity and polypharmacy with ADRs, and estimated local financial cost of admissions where an ADR was a contributing or main reason for admission with projected costs for NHS

SUBMITTER: Osanlou R 

PROVIDER: S-EPMC9255409 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature