Obesity and cancer death in white and black adults: A prospective cohort study.

ABSTRACT:

Objective

This study aimed to determine whether race modifies the association between obesity and cancer death.

Methods

The Pennington Center Longitudinal Study included 18,296 adults; 35.0% were male and 34.3% were Black. The primary end point was death from cancer.

Results

During a follow-up of 14.3 years, 346 cancer deaths occurred. Among men, race modified the association of BMI and cancer death (p_interaction = 0.045); compared with a BMI of 22 kg/m² , a BMI of 35 in White men was associated with a hazard ratio of 1.74 (95% CI: 1.38-2.21), and in Black men, the hazard ratio was 0.64 (95% CI: 0.45-0.90). Among women, race did not modify the association of BMI and cancer death (p_interaction =0.43); however, compared with a BMI of 22,

SUBMITTER: Brown JC 

PROVIDER: S-EPMC9256081 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature