Caging and photo-triggered uncaging of singlet oxygen by excited state engineering of electron donor-acceptor-linked molecular sensors.

ABSTRACT: Singlet oxygen (¹O₂), one of the most sought-after species in oxidative chemical reactions and photodynamic cancer therapy, is activated and neutralized in the atmosphere and living cells. It is essential to see "when" and "where" ¹O₂ is produced and delivered to understand and utilize it. There is an increasing demand for molecular sensor tools to capture, store, and supply ¹O₂, controlled by light and engineered singlet and triplet states, indicating the ¹O₂-capturing-releasing state. Here, we demonstrate the outstanding potential of an aminocoumarin-methylanthracene-based electron donor-acceptor molecule (1). Spectroscopic measurements confirm the formation of an endoperoxide (1-O₂) which

SUBMITTER: Sasikumar D 

PROVIDER: S-EPMC9256616 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature