Knowledge-based automatic plan optimization for left-sided whole breast tomotherapy.

ABSTRACT:

Background/purpose

Tomotherapy may deliver high-quality whole breast irradiation at static angles. The aim of this study was to implement Knowledge-Based (KB) automatic planning for left-sided whole breast using this modality.

Materials/methods

Virtual volumetric plans were associated to the dose distributions of 69 Tomotherapy (TT) clinical plans of previously treated patients, aiming to train a KB-model using a commercial tool completely implemented in our treatment planning system. An individually optimized template based on the resulting KB-model was generated for automatic plan optimization. Thirty patients of the training set and ten new patients were considered for internal/external validation. Fully-automatic plans (KB-TT) were generated and compared using the same g

SUBMITTER: Esposito PG 

PROVIDER: S-EPMC9256826 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature