Evolutionary Insights Into Microbiota Transplantation in Inflammatory Bowel Disease.

ABSTRACT: The intestinal microbiome plays an essential role in human health and disease status. So far, microbiota transplantation is considered a potential therapeutic approach for treating some chronic diseases, including inflammatory bowel disease (IBD). The diversity of gut microbiota is critical for maintaining resilience, and therefore, transplantation with numerous genetically diverse gut microbiota with metabolic flexibility and functional redundancy can effectively improve gut health than a single probiotic strain supplement. Studies have shown that natural fecal microbiota transplantation or washing microbiota transplantation can alleviate colitis and improve intestinal dysbiosis in IBD patients. However, unexpected adverse reactions caused by the complex and unclear composition of the flo

SUBMITTER: Wang X 

PROVIDER: S-EPMC9257068 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature