The Effects of Prenatal Exposure to Neighborhood Crime on Neonatal Functional Connectivity.

ABSTRACT:

Background

Maternal exposure to adversity during pregnancy has been found to affect infant brain development; however, the specific effect of prenatal crime exposure on neonatal brain connectivity remains unclear. Based on existing research, we hypothesized that living in a high-crime neighborhood during pregnancy would affect neonatal frontolimbic connectivity over and above other individual- and neighborhood-level adversity and that these associations would be mediated by maternal psychosocial stress.

Methods

Participants included 399 pregnant women, recruited as part of the eLABE (Early Life Adversity, Biological Embedding, and Risk for Developmental Precursors of Mental Disorders) study. In the neonatal period, 319 healthy, nonsedated infants were scanned using resting-s

SUBMITTER: Brady RG 

PROVIDER: S-EPMC9257309 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature