Characterization of multiple chemical components of GuiLingJi by UHPLC-MS and ¹H NMR analysis.

ABSTRACT: GuiLingJi (GLJ), a classic traditional Chinese medicine (TCM) formula, is composed of over 20 herbs, according to the Pharmacopeia of the People's Republic of China. Owing to its various activities, GLJ has been used in clinical settings for more than 400 years in China. However, the ambiguous chemical material basis limits the development of studies on the quality control and pharmacological mechanisms of GLJ. Therefore, comprehensive characterization of the multiple chemical components of GLJ is of great significance for the modernization of this formula. Given the great variety of herbs in GLJ, both UHPLC-MS and ¹H NMR techniques were employed in this study. In addition, solvent extraction with different polarities was used to eliminate signal interference and the concentrati

SUBMITTER: Shi J 

PROVIDER: S-EPMC9257439 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature