Nitrogen-doped carbon@TiO₂ double-shelled hollow spheres as an electrochemical sensor for simultaneous determination of dopamine and paracetamol in human serum and saliva.

ABSTRACT: As the most commonly used antipyretic and analgesic drug, paracetamol (PA) coexists with neurotransmitter dopamine (DA) in real biological samples. Their simultaneous determination is extremely important for human health, but they also interfere with each other. In order to improve the conductivity, adsorption affinity, sensitivity, and selectivity of TiO₂-based electrochemical sensor, N-doped carbon@TiO₂ double-shelled hollow sphere (H-C/N@TiO₂) is designed and synthesized by simple alcoholic and hydrothermal method, using polystyrene sphere (PS) as a template. Meanwhile, TiO₂ hollow spheres (H-TiO₂) or N-doped carbon hollow spheres (H-C/N) are also prepared by the same method. H-C/N@TiO₂ has good conductivity, charge separ

SUBMITTER: Yang H 

PROVIDER: S-EPMC9257442 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature