Site-specific Risk Stratification Models for Postoperative Recurrence and Survival Prediction in Patients with Upper Tract Urothelial Carcinoma Undergoing Radical Nephroureterectomy: Better Stratification for Adjuvant Therapy.

ABSTRACT:

Background

Site-specific postoperative risk models for localized upper tract urothelial carcinoma (UTUC) are unavailable.

Objective

To create specific risk models for renal pelvic urothelial carcinoma (RPUC) and ureteral urothelial carcinoma (UUC), and to compare the predictive accuracy with the overall UTUC risk model.

Design setting and participants

A multi-institutional database retrospective study of 1917 UTUC patients who underwent radical nephroureterectomy (RNU) between 2000 and 2018 was conducted.

Outcome measurements and statistical analysis

A multivariate hazard model was used to identify the prognostic factors for extraurinary tract recurrence (EUTR), cancer-specific death (CSD), and intravesical recurrence (IVR) after RNU. Patients were stratified i

SUBMITTER: Miyake M 

PROVIDER: S-EPMC9257658 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature