Idiopathic scoliosis: a systematic review and meta-analysis of heritability.

ABSTRACT:

Purpose

Idiopathic scoliosis is the most common spinal deformity and affects 1-3% of children and adolescents. Idiopathic scoliosis may run in families and the purpose of this systematic review was to describe the degree of heritability.

Methods

We searched Medline, Web of Science and EMBASE for family and twin studies reporting heritability estimates for idiopathic scoliosis, or studies from which heritability estimates could be calculated. Reference lists were screened for additional papers. We followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. The protocol was registered at PROSPERO (registration number: CRD42022307329).

Results

The literature search identified 1134 reports. After full-text screening, nine eligible reports w

SUBMITTER: Cheng T 

PROVIDER: S-EPMC9257730 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature