The Childhood Vaccination Schedule and the Lack of Association With Type 1 Diabetes.

ABSTRACT:

Objectives

Safety studies assessing the association between the entire recommended childhood immunization schedule and autoimmune diseases, such as type 1 diabetes mellitus (T1DM), are lacking. To examine the association between the recommended immunization schedule and T1DM, we conducted a retrospective cohort study of children born between 2004 and 2014 in 8 US health care organizations that participate in the Vaccine Safety Datalink.

Methods

Three measures of the immunization schedule were assessed: average days undervaccinated (ADU), cumulative antigen exposure, and cumulative aluminum exposure. T1DM incidence was identified by International Classification of Disease codes. Cox proportional hazards models were used to analyze associations between the 3 exposure measures

SUBMITTER: Glanz JM 

PROVIDER: S-EPMC9258424 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature