Nocturnal hypoxemia, blood pressure, vascular status and chronic mountain sickness in the highest city in the world.

ABSTRACT:

Introduction

Chronic mountain sickness (CMS) is a condition characterized by excessive erythrocytosis in response to chronic hypobaric hypoxia. CMS frequently triggers cardiorespiratory diseases such as pulmonary hypertension and right or left heart failure. Ambient hypoxia might be further amplified night-time by intermittent hypoxia related to sleep-disordered breathing (SDB) so that sleep disturbance may be an important feature of CMS. Our aim was to characterize in a cross-sectional study nocturnal hypoxaemia, SDB, blood pressure (BP), arterial stiffness and carotid intima-media thickness (CIMT) in highlanders living at extreme altitude.

Methods

Men aged 18 to 55 years were prospectively recruited. Home sleep apnoea test, questionnaires (short-form health survey; Montrea

SUBMITTER: Perger E 

PROVIDER: S-EPMC9258438 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature