Current state and future directions of genomic medicine in aortic dissection: A path to prevention and personalized care.

ABSTRACT: Aortic dissection confers high mortality and morbidity rates despite advances in treatment, impacts quality of life, and contributes immense burden to the healthcare system globally. Efforts to prevent aortic dissection through screening and management of modifiable risk factors and early detection of aneurysms should incorporate genomic information, as it is integral to stratifying risk. However, effective integration of genomic-guided risk assessment into clinical practice will require addressing implementation barriers that currently permeate our healthcare systems. The Aortic Dissection Collaborative was established to define aortic dissection research priorities through patient engagement. Using a collaborative patient-centered feedback model, our Genomic Medicine Working Group identi

SUBMITTER: Cecchi AC 

PROVIDER: S-EPMC9258522 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature