Viscosupplementation for knee osteoarthritis: systematic review and meta-analysis.

ABSTRACT:

Objective

To evaluate the effectiveness and safety of viscosupplementation for pain and function in patients with knee osteoarthritis.

Design

Systematic review and meta-analysis of randomised trials.

Data sources

Searches were conducted of Medline, Embase, and the Cochrane Central Register of Controlled Trials (CENTRAL) databases from inception to 11 September 2021. Unpublished trials were identified from the grey literature and trial registries.

Eligibility criteria for study selection

Randomised trials comparing viscosupplementation with placebo or no intervention for knee osteoarthritis treatment.

Main outcome measures

The prespecified primary outcome was pain intensity. Secondary outcomes were function and serious adverse events. Pain and function we

SUBMITTER: Pereira TV 

PROVIDER: S-EPMC9258606 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature