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Intensity modulated radiation therapy for definitive treatment of paraortic relapse in patients with endometrial cancer.


ABSTRACT:

Purpose

The paraortic nodes are a common site of recurrence of endometrial cancer, especially among patients previously treated with pelvic radiation. Intensity modulated radiation therapy (IMRT) can be used to deliver a tumoricidal dose to paraortic disease while minimizing dose to normal adjacent structures. In this study, we reviewed the outcomes of patients treated with IMRT for unresected or incompletely resected paraortic recurrences of primary uterine cancer.

Methods and materials

Between 2000 and 2009, 27 patients with unresected (19 patients) or incompletely resected (8 patients) paraortic relapse of endometrial cancer were treated with curative intent using IMRT. The paraortic basin was generally treated to a dose of 45-50 Gy, and gross disease was treated to a mea

SUBMITTER: Shirvani SM 

PROVIDER: S-EPMC9258613 | biostudies-literature | 2013 Jan-Mar

REPOSITORIES: biostudies-literature