Molecular Detection of Genetic Susceptibility to Bladder Cancer in Egyptian Patients.

ABSTRACT:

Objective

Genome-wide association studies (GWAS) have identified a number of genetic variants associated with the susceptibility of bladder cancer (BC) in European and Chinese populations. Here, we assessed the association of two of these variants, rs9642880 and rs710521 in an Egyptian patients and also examined the expression of c-Myc.The basis was due to the absence of studies on Egyptian patients to determine the association between rs9642880& rs710521 and bladder cancer risk, particularly due to the known role of the variant (rs9642880) in the Progression and development of bladder cancer.

Methods

Urine samples were collected from onehundred and fiftybladder cancer patients under particular standards and fifty healthy controls. Genomic DNA was extracted,  rs9642880 G>T a

SUBMITTER: Mamdouh S 

PROVIDER: S-EPMC9258647 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature