A fully implantable wireless bidirectional neuromodulation system for mice.

ABSTRACT: Novel research in the field of bioelectronic medicine requires neuromodulation systems that pair high-performance neurostimulation and bio-signal acquisition hardware with advanced signal processing and control algorithms. Although mice are the most commonly used animal in medical research, the size, weight, and power requirements of such bioelectronic systems either preclude use in mice or impose significant constraints on experimental design. Here, a fully-implantable recording and stimulation neuromodulation system suitable for use in mice is presented, measuring 2.2 cm³ and weighing 2.8 g. The bidirectional wireless interface allows simultaneous readout of multiple physiological signals and complete control over stimulation parameters, and a wirelessly rechargeable battery p

SUBMITTER: Wright JP 

PROVIDER: S-EPMC9258776 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature