Cholera diagnosis in human stool and detection in water: A systematic review and meta-analysis.

ABSTRACT:

Background

Cholera continues to pose a problem for low-resource, fragile and humanitarian contexts. Evidence suggests that 2.86 million cholera cases and 95,000 deaths due to cholera are reported annually. Without quick and effective diagnosis and treatment, case-fatality may be 50%. In line with the priorities of the Global Task Force on Cholera Control, we undertook a systematic review and meta-analysis of diagnostic test accuracy and other test characteristics of current tests for cholera detection in stool and water.

Methods

We searched 11 bibliographic and grey literature databases. Data was extracted on test sensitivity, specificity and other product information. Meta-analyses of sensitivity and specificity were conducted for tests reported in three or more studies. Wh

SUBMITTER: Falconer J 

PROVIDER: S-EPMC9258865 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature