Correlation between tuberculosis-specific interferon-γ release assay and intrathoracic calcification: A cross-sectional study.

ABSTRACT:

Background

Although persistent tuberculosis (TB) infection is known to cause calcification in the lungs, the relationship between intrathoracic calcification and the results of the interferon-γ release assay (IGRA) has not been fully elucidated. This study aimed to assess the association between intrathoracic calcification and IGRA results.

Methods

We retrospectively included consecutive patients who concurrently underwent chest X-ray, chest computed tomography (CT), and an IGRA. Patients with a current diagnosis of active TB or treatment history of active TB or latent tuberculosis infection (LTBI) were excluded. The association between calcification according to the chest X-ray or CT and IGRA results were analyzed using binomial logistic regression.

Results

This stud

SUBMITTER: Yamatani I 

PROVIDER: S-EPMC9258869 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature